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CBN (cannabinol) is a cannabinoid, which means it’s one of the active ingredients in marijuana. These are the compounds that make marijuana behave the way it does inside the brain and body.
The CBN oil, depending on the quantity required per evening, could provide sound sleep for up to 3 months.
CBN is a minor cannabinoid, which means it’s not initially present in marijuana in high concentrations the way THC and CBD usually are. The way marijuana creates CBN, however, makes this minor player truly stand out from all the rest.
Although some CBN (cannabinol) comes from the CBNA naturally present in cannabis, most often it comes from the THCA in the plant breaking down. When THCA oxidizes, it turns to CBNA. Like the other cannabinoids, when CBNA is heated, it loses its “A” and becomes CBN.
Very Little Psychoactivity
What does CBN do once the transformation from THC occurs? The biggest difference between these two cannabinoids is where they fall on the psychoactive spectrum. THC creates a euphoric, psychoactive high that’s marijuana’s most well-known side effect. CBN is barely psychoactive (and can only cause a high if ingested in very large doses).
While CBN doesn’t get people particularly high, it can make them sleepy. In fact, it’s known as the cannabinoid with the greatest sedative properties. Consuming 5 mg of CBN is the equivalent of taking 10 mg of Valium – but with only 10% of Valium’s psychoactive effects.
Good for Pain & Glaucoma
CBN/THC do share some similarities, however: both are excellent at killing pain, as well as reducing intra-ocular pressure in glaucoma patients. This spurred scientists to research various CBN effects to discover the medical potential of this cannabinoid.
As discussed above, cannabinol has made the most waves due to its particularly powerful sedative effects. It calms in a similar fashion to Valium but has very few its psychoactive effects, meaning that it can quell anxiety without leaving people feeling “spaced out” or unable to function. Many indica strains of marijuana have higher amounts of CBN (which may somewhat contribute to their sedative effects). However, these amounts are still in such small concentrations that the direct effect from CBN is still small unless the cannabinoid is concentrated.
Over the years, researchers have studied cannabinol and other cannabinoids as potentially effective anti-inflammatory drugs. CBN in particular works on the the pain-sensing TRPV2 receptor, but scientists believe it may also work on the CB2 receptor (which also transmits pain).
With strains of bacteria becoming increasingly resistant to antibiotics, doctors have been researching alternative ways to kill these dangerous organisms. Cannabinoids such as cannabinol are showing real promise as treatment for antibiotic-resistant strains of bacteria. In one study, THC, CBD, CBN, and other cannabinoids were shown effective at killing antibiotic-resistant MRSA strains of bacteria.
Like THC, CBN has been shown effective at reducing intra-ocular pressure in glaucoma patients. While it worked moderately well at reducing pressure after one dose, its effectiveness increased after repeated doses. Researchers did note that CBN caused ocular toxicity, however. THC also causes this problem, which is why many doctors advise their patients against using marijuana as a treatment for glaucoma – especially in the early stages of the disease.
Psoriasis is a painful condition that involves the overgeneration of skin cells (keratinocytes) and intense inflammation. Already proven to be an effective anti-inflammatory, CBN has also been studied for its ability to slow the overgrowth of skin cells at the affected site, making it an all-around good treatment for conditions like psoriasis.
Bone Tissue Growth
Scientists are also looking into cannabinol as a way to speed up the healing of bone fractures. CBN is showing the potential to be able to stimulate bone tissue growth; it does this by causing an indirect recruitment of mesencyzal stem cells from the surrounding bone marrow. These cells have the capability of turning into bone, as well as other tissue. While this doesn’t mean that doctors will be handing out marijuana joints as they put casts on bone fracture patients, it does show that concentrated CBN is a potentially helpful fracture treatment.
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Please never self-diagnose and always consult a an expert before starting treatment. We always try to keep up with the latest research, as insight into the benefits of cannabinoids is unfolding rapidly.
Note: All content is shared for personal information purposes, not as medical advice. Always consult your medical practitioner or specialist.